JD
Jonas Demeulemeester
VIB-KU Leuven Center for Cancer Biology, Research Foundation – Flanders (FWO), KU Leuven, The Francis Crick Institute
Research areas: Biochemistry, Genetics and Molecular Biology · Cancer Research · Cancer Genomics and Diagnostics · Chromatin Remodeling and Cancer · HIV Research and Treatment
0000-0002-2660-2478
Employment
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VIB-KU Leuven Center for Cancer Biology Group Leader2022 - Present
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Research Foundation – Flanders (FWO) Postdoctoral fellow2015 - Present
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Francis Crick Institute Postdoctoral fellow2015 - Present
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KU Leuven Research associate2013 - 2015
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Research Foundation – Flanders (FWO) Doctoral fellow2009 - 2013
Education
Projects & Funding
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Charting non-small cell lung cancer evolution and heterogeneity through multi-omics analysis and deconvolution Research Foundation - Flanders2020 - 2023
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Allele-specific Deconvolution of Tumour DNA Methylation and Expression Data to Reveal Underlying Cell Populations European Commission Horizon 20202016 - 2018
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Deconvolution of bulk tumour transcriptome and DNA methylation data to reveal underlying cell populations Research Foundation – Flanders (FWO)2015 - 2020
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Development of a novel antiviral strategy directed against the nuclear import of HIV Research Foundation – Flanders (FWO)2009 - 2013
Publications (86)
- The Clinicogenomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia Save
- Genomic–transcriptomic evolution in lung cancer and metastasis Save
- A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reveals the cellular and molecular impact of chromosome instability Save
- Single-cell Genome-and-Transcriptome sequencing without upfront whole-genome amplification reveals cell state plasticity of melanoma subclones Save
- Antibodies against endogenous retroviruses promote lung cancer immunotherapy Save
- Body composition and lung cancer-associated cachexia in TRACERx Save
- Lung adenocarcinoma promotion by air pollutants Save
- The evolution of lung cancer and impact of subclonal selection in TRACERx Save
- The evolution of non-small cell lung cancer metastases in TRACERx Save
- Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA Save
- System-wide mapping of neuropeptide-GPCR interactions inC. elegans Save
- Primary mediastinal large B‐cell lymphoma is characterized by large‐scale copy‐neutral loss of heterozygosity Save
- Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression. Save
- A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer. Save
- Biallelic mutations in cancer genomes reveal local mutational determinants Save
- A pan-cancer landscape of somatic mutations in non-unique regions of the human genome Save
- Analysis of long and short enhancers in melanoma cell states. Save
- A ubiquitous disordered protein interaction module orchestrates transcription elongation Save
- Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture Save
- Using DNA sequencing data to quantify T cell fraction and therapy response. Save