Toshinobu Nishimura

Employment

• Century Therapeutics LLC Scientific Expert
  2019 - Present
• Stanford University School of Medicine Basic Life Research Scientist
  2019 - 2019
• Stanford University School of Medicine Postdoctoral Researcher
  2014 - 2019
• The University of Tokyo Research Scientist
  2012 - 2014

Education

• The University of Tokyo Ph.D.
  2007 - 2012
• The University of Tokyo B.S.
  2003 - 2007

Projects & Funding

Projects & funding information is unavailable.

Publications (25)

• Data from Intra-Leukemic Interferon Signaling Suppresses Expansion and Mediates Chemoresistance in Human AML
  Daiki Karigane, Amy C. Fan, Toshinobu Nishimura

  +16 more

  • Kensuke Kayamori
  • Yusuke Nakauchi
  • Thomas Köhnke
  • Athreya S Rangavajhula
  • Asiri Ediriwickrema
  • +11 more
  2026 DOI: 10.1158/2643-3230.c.8239498
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• Intra-Leukemic Interferon Signaling Suppresses Expansion and Mediates Chemoresistance in Human AML
  Daiki Karigane, Amy C. Fan, Toshinobu Nishimura +16 more
  Blood Cancer Discovery 2026 DOI: 10.1158/2643-3230.BCD-25-0173
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• Supplementary Figure S1-S8 from Intra-Leukemic Interferon Signaling Suppresses Expansion and Mediates Chemoresistance in Human AML
  Daiki Karigane, Amy C. Fan, Toshinobu Nishimura

  +16 more

  • Kensuke Kayamori
  • Yusuke Nakauchi
  • Thomas Köhnke
  • Athreya S Rangavajhula
  • Asiri Ediriwickrema
  • +11 more
  2026 DOI: 10.1158/2643-3230.31046968
  +Save
• Supplementary Table S1-S4 from Intra-Leukemic Interferon Signaling Suppresses Expansion and Mediates Chemoresistance in Human AML
  Daiki Karigane, Amy C. Fan, Toshinobu Nishimura

  +16 more

  • Kensuke Kayamori
  • Yusuke Nakauchi
  • Thomas Köhnke
  • Athreya S Rangavajhula
  • Asiri Ediriwickrema
  • +11 more
  2026 DOI: 10.1158/2643-3230.31046965
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• Development of iPSC-Derived T Cells Targeting EGFR Neoantigens in Non-Small Cell Lung Cancer
  2025 DOI: 10.1101/2025.02.15.638388
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• Genome engineering with Cas9 and AAV repair templates generates frequent concatemeric insertions of viral vectors
  Fabian Patrik Suchy, Daiki Karigane, Yusuke Nakauchi +13 more
  Nature Biotechnology 2025 DOI: 10.1038/s41587-024-02171-w
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• Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells.
  Toshinobu Nishimura, Haojun Xu, 正幸 岩崎 +13 more
  Gene therapy 2020 DOI: 10.1038/s41434-020-0179-z
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• Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase.
  Mark C. Wilkes, Kavitha Siva, Jun Chen +18 more
  Nature communications 2020 DOI: 10.1038/s41467-020-17100-z
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• Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards.
  Renata M. Martin, Jonas L. Fowler, M. Kyle Cromer +6 more
  Nature communications 2020 DOI: 10.1038/s41467-020-16455-7
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• Use of polyvinyl alcohol for chimeric antigen receptor T-cell expansion.
  Toshinobu Nishimura, Ian Hsu, Daniel Martinez-Krams

  +5 more

  • Yusuke Nakauchi
  • Ravindra Majeti
  • Satoshi Yamazaki
  • Hiromitsu Nakauchi
  • Adam C. Wilkinson
  Experimental hematology 2019 DOI: 10.1016/j.exphem.2019.11.007
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• Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination.
  Renata M. Martin, Kazuya Ikeda, M. Kyle Cromer +18 more
  Cell stem cell 2019 DOI: 10.1016/j.stem.2019.04.001
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• Generation of Antigen-Specific T Cells from Human Induced Pluripotent Stem Cells.
  Methods in molecular biology (Clifton, N.J.) 2019 DOI: 10.1007/978-1-4939-8938-6_3
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• Human iPSC Generation from Antigen-Specific T Cells.
  Methods in molecular biology (Clifton, N.J.) 2019 DOI: 10.1007/978-1-4939-9728-2_5
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• Using the Inducible Caspase-9 Suicide-Safeguard System with iPSC and Bioluminescent Tracking.
  Methods in molecular biology (Clifton, N.J.) 2019 DOI: 10.1007/978-1-4939-9728-2_20
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• Efficient scarless genome editing in human pluripotent stem cells.
  Kazuya Ikeda, Nobuko Uchida, Toshinobu Nishimura +6 more
  Nature methods 2018 DOI: 10.1038/s41592-018-0212-y
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• Thalidomide induces apoptosis in undifferentiated human induced pluripotent stem cells.
  In vitro cellular & developmental biology. Animal 2017 DOI: 10.1007/s11626-017-0192-8
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• Functional Analysis of Dendritic Cells Generated from T-iPSCs from CD4+ T Cell Clones of Sjögren's Syndrome.
  Stem cell reports 2017 DOI: 10.1016/j.stemcr.2017.04.010
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• An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors.
  Stem cell reports 2017 DOI: 10.1016/j.stemcr.2017.01.015
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• Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.
  Mark Ping Chao, Andrew J. Gentles, Susmita Chatterjee +15 more
  Cell stem cell 2017 DOI: 10.1016/j.stem.2016.11.018
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• Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos.
  Hideki Masaki, Megumi Kato‐Itoh, Yusuke Takahashi +12 more
  Cell stem cell 2016 DOI: 10.1016/j.stem.2016.10.013
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