Dr. Ansab Akhtar
Louisiana State University Health Sciences Center New Orleans, University of Petroleum and Energy Studies, Panjab University, National Institute of Pharmaceutical Education and Research Hyderabad
Research areas: Neuroscience · Cellular and Molecular Neuroscience · Alzheimer's disease research and treatments · Dementia and Cognitive Impairment Research · Neuroinflammation and Neurodegeneration Mechanisms
0000-0002-4839-4454
About
Dr. Ansab Akhtar is a neuroscientist and pharmacologist specializing in preclinical and translational research on neurodegenerative, neurodevelopmental, and psychiatric disorders. He recently served as a Postdoctoral Research Fellow at the Neuroscience Center of Excellence, Louisiana State University Health Sciences Center (LSUHSC), New Orleans, USA. He earned his Ph.D. in Pharmacology from Panjab University, Chandigarh.
His research focuses on cognitive neuroscience and the molecular and cellular mechanisms underlying brain disorders. His work has extensively explored pathways associated with brain insulin resistance, oxidative stress, mitochondrial dysfunction, cholinergic deficits, and neuroinflammation. His doctoral research investigated brain insulin resistance in the intracerebroventricular streptozotocin (ICV-STZ)-induced rat model of Alzheimer’s disease.
In addition to Alzheimer’s disease research, Dr. Akhtar has contributed to studies involving Parkinson’s disease, Huntington’s disease, Schizophrenia, Depression, post-traumatic stress disorder (PTSD), diabetic cognitive impairment, and neuropathy. He has authored and co-authored several peer-reviewed research and review articles published in international scientific journals.
His earlier academic training included research on the cloning, expression, and purification of recombinant proteins using bacterial expression systems. He also served as an Assistant Professor at UPES, where he taught Pharmacology, Human Anatomy & Physiology, and Clinical Research.
Dr. Akhtar possesses extensive expertise in animal handling and behavioral neuroscience, including stereotaxic surgeries and the development of experimental models of neurodegenerative disorders. His technical proficiency includes molecular biology techniques such as ELISA, Western blotting, PCR, qRT-PCR, immunohistochemistry, confocal microscopy, fluorescence imaging, histology, and biochemical assays related to neuroinflammation, oxidative stress, and mitochondrial dysfunction. He is experienced in data analysis using GraphPad Prism and biostatistical methods including t-tests, ANOVA, and post-hoc analyses.
He has participated in several international conferences, workshops, and neuroscience training programs, including Sfn Neuroscience meeting, IBRO-APRC Schools, the FENS Virtual Forum, and ICONICA 2020, where he presented research on sodium orthovanadate-mediated cognitive improvement in ICV-STZ rats. He has also contributed to scientific outreach and education activities, including volunteering as a laboratory demonstrator during the DST-INSPIRE Internship Camp at Panjab University.
His primary research interests include cognitive neuroscience, neurodegenerative diseases and related dementias, pharmacology and toxicology, molecular mechanisms of brain disorders, and translational preclinical research.
Employment
-
Louisiana State University Health Sciences Center New Orleans Postdoctoral research fellow2024 - 2026
-
University of Petroleum and Energy Studies Assistant Professor2022 - 2024
-
Daiichi Sankyo (India) Project trainee2014 - 2015
Education
- 2016 - 2021
-
National Institute of Pharmaceutical Education and Research Hyderabad M.S.2013 - 2015
-
Jamia Hamdard Faculty of Pharmacy B.Pharmacy2008 - 2012
Projects & Funding
-
Improvement of cognitive functions by L-leucine via mTOR/PI3K/AKT pathway in Drosophila model of Alzheimer’s disease University of Petroleum and Energy Studies2022 - 2024
-
Neuroscience 2021 International Brain Research Organization2021 - 2021
-
Maulana Azad National Fellowship University Grants Commission2016 - Present
Publications (45)
- Drug-Induced Reduction in 80Q Aggregates in a Dictyostelium discoideum Model of PolyQ Disease Save
- Neurovascular Uncoupling in Alzheimer’s and Parkinson’s Diseases: Mechanisms and Therapeutic Strategies Save
- Parkinson’s Disease: Conventional Pharmacotherapy, Drug Delivery Innovations, and Emerging Therapeutic Targets Save
- Neuroimmune Interactions in Neurodegeneration: The Role of Microglia in Alzheimer’s and Parkinson’s Disease Pathogenesis Save
- Preclinical models for autism spectrum disorder: past, present, and future Save
- Editorial: Bridging Inflammation, Oxidative Stress, and Metabolic Dysfunction in Brain Disorders Save
- Flavonoid-Based Combination Therapies and Nano-Formulations: An Emerging Frontier in Breast Cancer Treatment Save
- The Interplay of Oxidative Stress, Mitochondrial Dysfunction, and Neuroinflammation in Autism Spectrum Disorder: Behavioral Implications and Therapeutic Strategies Save
- Exploring hepatic stellate cell-driven fibrosis: therapeutic advances and future perspectives Save
- Change of Spiny Neuron Structure in the Basal Ganglia Song Circuit and Its Regulation by miR-9 during Song Development Save
- Nutritional, Phytochemical, and Antimicrobial Properties of Carica papaya Leaves: Implications for Health Benefits and Food Applications Save
- Vitamin-D as a multifunctional molecule for overall well-being: An integrative review Save
- The Utilisation of Mushroom Leftovers, Oats, and Lactose-Free Milk Powder for the Development of Geriatric Formulation Save
- Types of memory, dementia, Alzheimer’s disease, and their various pathological cascades as targets for potential pharmacological drugs Save
- Targeting angiogenesis, inflammation, and oxidative stress in depression Save
- Biochanin A Chemistry, Structural Modifications, and Therapeutic Applications: An Update Save
- Chromium and Alzheimer's disease Save
- Repurposing Anti-inflammatory Agents in the Potential Treatment of SARS-COV-2 Infection Save
- Sarcosine (glycine transporter inhibitor) attenuates behavioural and biochemical changes induced by ketamine, in the rat model of schizophrenia Save
- Preclinical Models for Alzheimer’s Disease: Past, Present, and Future Approaches Save